Brief Communication

Brief communication: Mitochondrial haplotype C4c confirmed as a founding genome in the Americas

  1. Ripan S. Malhi1,*,
  2. Jerome S. Cybulski2,
  3. Raul Y. Tito3,
  4. Jesse Johnson4,
  5. Harold Harry5,
  6. Carrie Dan6

Article first published online: 21 DEC 2009

DOI: 10.1002/ajpa.21238

Issue

American Journal of Physical Anthropology

American Journal of Physical Anthropology

Volume 141, Issue 3, pages 494–497, March 2010

Additional Information

How to Cite

Malhi, R. S., Cybulski, J. S., Tito, R. Y., Johnson, J., Harry, H. and Dan, C. (2010), Brief communication: Mitochondrial haplotype C4c confirmed as a founding genome in the Americas. Am. J. Phys. Anthropol., 141: 494–497. doi: 10.1002/ajpa.21238

Author Information

  1. 1

    Department of Anthropology, Animal Biology and Institute for Genomic Biology, University of Illinois Urbana-Champaign, IL

  2. 2

    Canadian Museum of Civilization, Gatineau, Quebec, Canada

  3. 3

    Department of Anthropology, University of Oklahoma, Norman

  4. 4

    Department of Animal Biology, University of Illinois Urbana-Champaign, IL

  5. 5

    Stswécemc/Xgat'temc Indian Band, British Columbia, Canada

  6. 6

    Tk'emlups Indian Band, British Columbia, Canada

*Department of Anthropology, University of Illinois Urbana-Champaign, 209F Davenport Hall, 607 Matthews Avenue, Urbana, IL 61801

Publication History

  1. Issue published online: 1 FEB 2010
  2. Article first published online: 21 DEC 2009
  3. Manuscript Accepted: 23 OCT 2009
  4. Manuscript Received: 26 JUN 2009

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Keywords:

  • Native American;
  • peopling of the Americas;
  • mtDNA

Abstract

Mitochondrial DNA analysis of 31 unrelated Shuswap speakers from a previously poorly sampled region of North America revealed two individuals with haplogroups rarely found in the Americas, C4c and C1d. Comparison of the complete genomes of the two individuals with others found in the literature confirms that C4c is a founding haplotype and gives insight into the evolution of the C1d haplotype. This study demonstrates the importance of collecting and analyzing data from Native North Americans when addressing hypotheses about the peopling of the Americas. Am J Phys Anthropol, 2010. © 2009 Wiley-Liss, Inc.

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