Potential conflict of interest: J.J.G. has no disclosures. J.H.A. serves on the Scientific Advisory Board for Entellus Medical; he also holds stock options with Entellus Medical and Entrigue Surgical. D.J.F. has no disclosures. R.B.K. is a consultant for Entrigue Surgical and holds stock options.
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Original Article
Clinical evaluation of a bioresorbable implant for medialization of the middle turbinate in sinus surgery†
Article first published online: 19 NOV 2010
DOI: 10.1002/alr.20001
Copyright © 2011 American Rhinologic Society-American Academy of Otolaryngic Allergy, LLC
Issue
International Forum of Allergy & Rhinology
Volume 1, Issue 1, pages 33–37, January/February 2011
Additional Information
How to Cite
Grisel, J. J., Atkins, J. H., Fleming, D. J. and Kuppersmith, R. B. (2011), Clinical evaluation of a bioresorbable implant for medialization of the middle turbinate in sinus surgery. International Forum of Allergy & Rhinology, 1: 33–37. doi: 10.1002/alr.20001
- †
Publication History
- Issue published online: 25 FEB 2011
- Article first published online: 19 NOV 2010
- Manuscript Accepted: 5 AUG 2010
- Manuscript Revised: 22 JUL 2010
- Manuscript Received: 18 MAY 2010
- Abstract
- Article
- References
- Cited By
Keywords:
- sinus surgery;
- bioresorbable;
- sinusitis;
- endoscopic;
- middle turbinate;
- implant
Abstract
Background
During endoscopic sinus surgery (ESS), postoperative lateralization of the middle turbinate can lead to scarring and obstruction of key drainage pathways, including the osteomeatal complex. The technique of suturing the middle turbinate to the nasal septum to enhance exposure can be difficult and time consuming. This study presents the first clinical results using the Middle Turbinate Implant (MTI), a device composed of absorbable copolymer polylactide-co-glycolide and intended to medialize the middle turbinate during surgical procedures such as ESS.
Methods
The trial included 22 implantations (21 successful implantations) on 14 subjects (6 unilateral and 8 bilateral implantations). The primary outcome measure was the position of the middle turbinate at 1, 2, and 4 weeks postoperatively. The extent of tissue reaction at the site of implantation was also evaluated.
Results
At 1, 2, and 4 weeks postoperatively, 100% of the middle turbinates were held medially or in the neutral position with no significant synechiae present. At 1, 2, and 4 weeks postoperatively, there was either no (95%, 90%, and 95%) or mild (5%, 10%, and 5%) tissue reaction at the site of implantation. No complications were noted during implantation.
Conclusion
The use of the bioresorbable MTI appears to be a safe and effective method of medializing the middle turbinate during ESS. © 2011 ARS-AAOA, LLC.