Funding source for the study: Scott & White Research Grants Program at Texas A&M as a Research Advancement Award (“A Human Study Model for Research in Sinonasal Disease”; Scott & White Institutional Review Board Registration #IRB00000706 Project ID# 90344 to AG).
The aerodynamics of the sinonasal interface: the nose takes wing—a paradigm shift for our time
Article first published online: 5 NOV 2012
© 2013 ARS-AAOA, LLC
International Forum of Allergy & Rhinology
Volume 3, Issue 4, pages 299–306, April 2013
How to Cite
How to Cite this Article: The aerodynamics of the sinonasal interface: the nose takes wing—a paradigm shift for our time. Int Forum Allergy Rhinol, 2013; 3:299–306.
Potential conflict of interest: None provided.
- Issue published online: 8 APR 2013
- Article first published online: 5 NOV 2012
- Manuscript Accepted: 18 AUG 2012
- Manuscript Revised: 26 JUN 2012
- Manuscript Received: 5 APR 2012
- nasal aerodynamics;
- nitric oxide;
- sinonasal gas exchange;
- Venturi effect;
- Bernoulli principle;
- sinus surgery;
- sinonasal interface
Ventilation of and gas exchange between the nose and the paranasal sinuses are believed to occur by convection and diffusion based on experiments that neglect the effects of physiological respiration and aerodynamic forces at the sinonasal interface (SNI). Based on these experiments, the exchange of gas is presumed to be slow, and principally dependent on gas concentration and diameter, number, and location of ostia.
In 12 healthy adult volunteers, real-time sinus nitric oxide measurements were obtained with catheters placed through natural ostia during respiratory maneuvers.
The nose is a masterful collection of aerodynamic foils and channels designed to accomplish powered sinonasal gas exchange and ventilation within a few seconds during each inspiration.
The new perspective on the functional anatomy of the SNI demands a paradigm shift that is followed by physiological, medical, and surgical implications and a radical change in our perception and understanding.