Polypoid changes of the middle turbinate as an indicator of atopic disease

Authors

  • Laura J. White MD,

    1. Department of Otolaryngology—Head and Neck Surgery, School of Medicine, Emory University, Atlanta, GA
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  • Melissa R. Rotella BSN, MSN, FNP-C,

    1. Emory University Sinus, Nasal, and Allergy Center, Department of Otolaryngology–Head and Neck Surgery, Emory University, Atlanta, GA
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  • John M. DelGaudio MD

    Corresponding author
    1. Department of Otolaryngology—Head and Neck Surgery, School of Medicine, Emory University, Atlanta, GA
    • Correspondence to: John M. DelGaudio, MD, Emory University School of Medicine, Department of Otolaryngology–Head and Neck Surgery, 550 Peachtree Street NE, Atlanta, GA 30308; e-mail: jdelgau@emory.edu

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  • Potential conflict of interest: None provided.

Abstract

Background

High levels of local immunoglobulin E (IgE) have been demonstrated in nasal polypoid tissue; however, an association between nasal polyps and allergy has not been proven. The authors have observed that polypoid edema isolated to the leading edge of the middle turbinate (MT) is highly associated with allergic rhinitis. The objective of this study was to determine if there is an association between isolated MT polyps and inhalant allergy.

Methods

A single institution prospective study was performed. Twenty-five consecutive patients found to have isolated MT polyps on endoscopic exam were recruited. Nasal and allergy symptoms were documented on the intake form. Allergy testing was recommended to all patients.

Results

Of the 25 patients found to have isolated MT polypoid edema documented on endoscopic exam, 16 patients underwent skin or in vitro allergy testing. All of the patients tested positive for inhalant allergy.

Conclusion

This small series provides strong evidence to support an association between isolated MT polypoid edema and allergy. We recommend allergy testing in all patients with isolated MT polyps or polypoid edema.

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