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Safety and Perioperative Adverse Events in Pediatric Endoscopic Sinus Surgery: An ACS-NSQIP-P Analysis

Authors

  • Christopher R. Roxbury MD,

    1. Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
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  • Lilun Li MD,

    1. Department of Otolaryngology-Head and Neck Surgery, George Washington University School of Medicine, Washington, DC, USA
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  • Daniel Rhee MD,

    1. Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
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  • Kris R. Jatana MD,

    1. Department of Otolaryngology-Head and Neck Surgery, Nationwide Children's Hospital and Wexner Medical Center at Ohio State University, Columbus, OH, USA
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  • Rahul K Shah MD MBA,

    1. Department of Otolaryngology-Head and Neck Surgery, George Washington University School of Medicine, Washington, DC, USA
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  • Emily F. Boss MD MPH

    Corresponding author
    1. Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    • Correspondence to: Emily F. Boss, MD MPH, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins Outpatient Center, 601 N. Caroline St, 6th Floor, Baltimore, MD 21287, Phone: 410-955-9772, e-mail: erudnic1@jhmi.edu

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  • Disclosures: EFB is supported by the Agency for Healthcare Research and Quality Grant #1K08 HS22932-01, the Johns Hopkins Clinician Scientist Award, and the American Society of Pediatric Otolaryngology Career Development Award

  • Presented at the American Rhinologic Society at the Combined Otolaryngologic Spring Meeting in San Diego, CA, April 26–27 2017

Abstract

Introduction

This study describes safety outcomes of pediatric endoscopic sinus surgery (ESS) to identify risk factors for 30-day postoperative adverse events using the National Surgical Quality Improvement Program–Pediatric (NSQIP-P) database.

Methods

We performed a retrospective cohort study involving patients in the 2012–2015 NSQIP-P database who underwent ESS. Predictors included demographics, comorbidities and surgical acuity. Outcomes included 30-day complications, reoperations, and readmissions.

Results

Among 2,061 ESS cases identified, 1,829 (88.7%) were elective and 232 (11.3%) were urgent/emergent. There were 92 (4.5%) readmissions, 54 (2.6%) unplanned reoperations, and 61 (3.0%) complications. On multivariate analysis, readmission was associated with urgent/emergent procedures (OR 2.31, CI 1.36-3.93, p<0.01) and history of bleeding disorder (OR 2.24, CI 1.12-4.44, p = 0.02), reoperation was associated with urgent/emergent procedures (OR 5.78, CI 3.24-10.34, p<0.01), and complications were associated with urgent/emergent procedures (OR 3.81, CI 2.13-6.82, p<0.01) and history of bleeding disorder (OR 5.30, CI 2.74-10.20, p<0.01). Bleeding requiring transfusion was associated with urgent/emergent procedures (OR 9.61, CI 2.90-31.80, p<0.01), history of bleeding disorder (OR 14.16, CI 4.41-45.45, p<0.01), and age <3 years (OR 3.92, CI 0.99-15.61, p = 0.05). Black children were significantly more likely to undergo urgent/emergent surgery than white children (19.7% vs. 9.6%, p<0.01).

Conclusions

This multi-institutional study confirms that while pediatric ESS is largely safe, urgent/emergent procedures carry the greatest risk of postoperative adverse events, and black children are significantly more likely to undergo higher acuity surgery than white children. Regardless of procedure acuity, young age and bleeding disorder are associated with higher risk of 30-day adverse events.

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