Original Article

Taurine deficiency is a cause of vigabatrin-induced retinal phototoxicity†

  1. Firas Jammoul MD1,2,‡,
  2. Qingping Wang MD1,2,3,‡,
  3. Rima Nabbout MD, PhD4,5,6,
  4. Caroline Coriat MD1,2,
  5. Agnès Duboc PhD1,2,
  6. Manuel Simonutti1,2,
  7. Elisabeth Dubus1,2,10,
  8. Cheryl M. Craft PhD7,
  9. Wen Ye MD3,
  10. Stephen D. Collins MD, PhD8,
  11. Olivier Dulac MD4,5,6,
  12. Catherine Chiron MD, PhD4,5,6,
  13. José A. Sahel MD1,2,9,10,
  14. Serge Picaud PhD1,2,10,11,*

Article first published online: 4 FEB 2009

DOI: 10.1002/ana.21526

Issue

Annals of Neurology

Annals of Neurology

Volume 65, Issue 1, pages 98–107, January 2009

Additional Information

How to Cite

Jammoul, F., Wang, Q., Nabbout, R., Coriat, C., Duboc, A., Simonutti, M., Dubus, E., Craft, C. M., Ye, W., Collins, S. D., Dulac, O., Chiron, C., Sahel, J. A. and Picaud, S. (2009), Taurine deficiency is a cause of vigabatrin-induced retinal phototoxicity. Ann Neurol., 65: 98–107. doi: 10.1002/ana.21526

Author Information

  1. 1

    Institut National de la Sante et de la Recherche Médicale, U592, Institut de la Vision, Paris, France

  2. 2

    Université Pierre et Marie Curie-Paris6, UMR-S 592, Paris, France

  3. 3

    Ophthalmology Department, Fudan University, Huashan Hospital, Shanghai, China

  4. 4

    Institut National de la Sante et de la Recherche Médicale, U663, Paris France

  5. 5

    University Paris Descartes, Paris France

  6. 6

    Assistance Publique-Hopitaux de Paris, Hopital Necker, Service de Neuropédiatrie, Paris, France

  7. 7

    Departments of Ophthalmology and Cell & Neurobiology, Keck School of Medicine of the University of Southern California, and Mary D. Allen Laboratory for Vision Research, Doheny Eye Institute, Los Angeles, CA

  8. 8

    NeuroTherapeutics Pharmaceuticals, Chicago, IL

  9. 9

    Centre Hospitalier National d'Ophtalmologie des quinze-vingts, Paris France

  10. 10

    Fondation Ophtalmologique Adolphe de Rothschild, Paris France

  11. 11

    Assistance Publique-Hopitaux de Paris, Paris, France

  1. ‡

    F.J. and Q.W. contributed equally to this work.

*INSERM U-592, Institut de la Vision, 17 rue Moreau, 75012 Paris, France

  1. †

    Potential conflict of interest: Nothing to report.

Publication History

  1. Issue published online: 12 FEB 2009
  2. Article first published online: 4 FEB 2009
  3. Manuscript Accepted: 18 AUG 2008
  4. Manuscript Revised: 25 JUL 2008
  5. Manuscript Received: 5 JUN 2008

Funded by

  • Institut National de la Sante et de la Recherche Médicale
  • Université Pierre et Marie Curie (Paris VI)
  • Fondation Ophtalmologique A. de Rothschild (Paris)
  • Agence Nationale pour la Recherche (ANR: GABARET)
  • Fédération des Aveugles de France
  • European Economic Community. Grant Number: EVI-GENORET-512036
  • Ovation Pharmaceuticals (USA)
  • Fellowship from the city of Paris
  • University of Tichcrine (Syria;
  • Mary D. Allen Laboratory for Vision Research
  • Doheny Eye Institute (DEI)
  • NIH National Eye Institute (NEI). Grant Numbers: EY015851, EY03040 [DEI Core Grant]
  • RPB

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (1609K)

Options for accessing this content:

  • If you have access to this content through a society membership, please first log in to your society website.
  • If you would like institutional access to this content, please recommend the title to your librarian.
  • Login via Athens http://onlinelibrary.wiley.com/athens or other institutional login options http://onlinelibrary.wiley.com/login-options .
  • You can purchase online access to this Article for a 24-hour period (price varies by title)
    • If you already have a Wiley Online Library or Wiley InterScience user account: login above and proceed to purchase the article.
    • New Users: Please register, then proceed to purchase the article.

Please register to:

  • Save publications, articles and searches
  • Get email alerts
  • Get all the benefits mentioned below!

Register now >

View Full Article (HTML) Get PDF (1609K)