Original Article

Apolipoprotein E–dependent accumulation of Alzheimer disease–related lesions begins in middle age†

  1. Eloise Kok BScHons1,2,*,
  2. Satu Haikonen MD1,2,
  3. Teemu Luoto MD1,2,
  4. Heini Huhtala MSc3,
  5. Sirkka Goebeler MD1,2,
  6. Hannu Haapasalo MD, PhD4,
  7. Pekka J. Karhunen MD, PhD1,2

Article first published online: 18 MAR 2009

DOI: 10.1002/ana.21696

Issue

Annals of Neurology

Annals of Neurology

Volume 65, Issue 6, pages 650–657, June 2009

Additional Information

How to Cite

Kok, E., Haikonen, S., Luoto, T., Huhtala, H., Goebeler, S., Haapasalo, H. and Karhunen, P. J. (2009), Apolipoprotein E–dependent accumulation of Alzheimer disease–related lesions begins in middle age. Ann Neurol., 65: 650–657. doi: 10.1002/ana.21696

Author Information

  1. 1

    Department of Forensic Medicine, Medical School, University of Tampere, Tampere, Finland

  2. 2

    Center for Laboratory Medicine, Tampere University Hospital, Tampere, Finland

  3. 3

    School of Public Health, Medical School, University of Tampere, Tampere, Finland

  4. 4

    Department of Pathology, Center for Laboratory Medicine, Tampere University Hospital, Tampere, Finland

*University of Tampere, Medical School, FIN-33014, Tampere, Finland

  1. †

    Potential conflict of interest: All authors declare that they have no competing interests.

Publication History

  1. Issue published online: 25 JUN 2009
  2. Article first published online: 18 MAR 2009
  3. Accepted manuscript online: 18 MAR 2009 12:00AM EST
  4. Manuscript Accepted: 27 FEB 2009
  5. Manuscript Revised: 3 FEB 2009
  6. Manuscript Received: 15 NOV 2007

Funded by

  • Medical Research Fund of Tampere University Hospital
  • Pirkanmaa Regional Fund of the Finnish Cultural Foundation
  • Finnish Foundation for Cardiovascular Research
  • Yrjö Jahnsson Foundation

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