• Please log in or register to access this feature.

Original Article

Resting interhemispheric functional magnetic resonance imaging connectivity predicts performance after stroke

  1. Alex R. Carter MD, PhD1,†,
  2. Serguei V. Astafiev PhD2,‡,
  3. Catherine E. Lang PhD1,3,4,§,
  4. Lisa T. Connor PhD1,2,4,¶,
  5. Jennifer Rengachary MSOT1,‖,
  6. Michael J. Strube PhD3,5,††,
  7. Daniel L. W. Pope BS2,‡‡,
  8. Gordon L. Shulman PhD1,§§,
  9. Maurizio Corbetta MD1,2,6,§§,*

Article first published online: 27 OCT 2009

DOI: 10.1002/ana.21905

Issue

Annals of Neurology

Annals of Neurology

Volume 67, Issue 3, pages 365–375, March 2010

Additional Information

How to Cite

Carter, A. R., Astafiev, S. V., Lang, C. E., Connor, L. T., Rengachary, J., Strube, M. J., Pope, D. L. W., Shulman, G. L. and Corbetta, M. (2010), Resting interhemispheric functional magnetic resonance imaging connectivity predicts performance after stroke. Ann Neurol., 67: 365–375. doi: 10.1002/ana.21905

Author Information

  1. 1

    Department of Neurology, Washington University School of Medicine, St. Louis, MO

  2. 2

    Department of Radiology, Washington University School of Medicine, St. Louis, MO

  3. 3

    Program in Physical Therapy, Washington University School of Medicine, St. Louis, MO

  4. 4

    Program in Occupational Therapy, Washington University School of Medicine, St. Louis, MO

  5. 5

    Department of Psychology, Washington University in St. Louis, St. Louis, MO

  6. 6

    Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, MO

  1. †

    A.R.C. performed the analysis of most imaging data (BOLD functional connectivity analysis and stroke lesion segmentation analysis), imaging-behavior correlations, and statistical analysis, assisted in the recruitment and scanning of subjects, and wrote the paper.

  2. ‡

    S.V.A. assisted in the scanning of subjects, image analysis, ROI creation, and encoding of behavioral data, and developed the composite functional connectivity scores.

  3. §

    C.E.L. contributed to the experimental design and development of an appropriate battery for testing motor behavior.

  4. L.T.C. contributed to the experimental design and behavioral battery and helped with the statistical analysis.

  5. ‖

    J.R. recruited and obtained consent from patients, assisted in the scanning, administered the behavioral battery, and analyzed the behavioral data.

  6. ††

    M.J.S. instructed the authors in statistical methods for comparing nonindependent correlations.

  7. ‡‡

    D.L.W.P. assisted in scanning and behavioral testing.

  8. §§

    G.L.S. and M.C. designed the study, oversaw data acquisition and analysis, and were principal editors of the paper. All authors discussed the results and commented on the paper.

*Departments of Neurology, Radiology, and Anatomy and Neurobiology, Washington University, Box 8111, 4525 Scott Ave, Saint Louis, MO 63110

  1. †

    A.R.C. performed the analysis of most imaging data (BOLD functional connectivity analysis and stroke lesion segmentation analysis), imaging-behavior correlations, and statistical analysis, assisted in the recruitment and scanning of subjects, and wrote the paper.

  2. ‡

    S.V.A. assisted in the scanning of subjects, image analysis, ROI creation, and encoding of behavioral data, and developed the composite functional connectivity scores.

  3. §

    C.E.L. contributed to the experimental design and development of an appropriate battery for testing motor behavior.

  4. L.T.C. contributed to the experimental design and behavioral battery and helped with the statistical analysis.

  5. ‖

    J.R. recruited and obtained consent from patients, assisted in the scanning, administered the behavioral battery, and analyzed the behavioral data.

  6. ††

    M.J.S. instructed the authors in statistical methods for comparing nonindependent correlations.

  7. ‡‡

    D.L.W.P. assisted in scanning and behavioral testing.

  8. §§

    G.L.S. and M.C. designed the study, oversaw data acquisition and analysis, and were principal editors of the paper. All authors discussed the results and commented on the paper.

Publication History

  1. Issue published online: 29 MAR 2010
  2. Article first published online: 27 OCT 2009
  3. Accepted manuscript online: 27 OCT 2009 12:00AM EST
  4. Manuscript Accepted: 20 OCT 2009
  5. Manuscript Revised: 12 OCT 2009
  6. Manuscript Received: 14 APR 2009

Funded by

  • National Institute of Mental Health. Grant Number: R01 MH71920-06
  • National Institute of Neurological Disorders and Stroke. Grant Numbers: R01 NS48013, R01 HD061117-05A2, 1K08NS064365-01A1
  • Robert Wood Johnson Foundation Amos Faculty Development Program
  • James S. McDonnell Foundation in supporting the Cognitive Rehabilitation Research Group
  • Rehabilitation Institute of St. Louis

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article with Supporting Information (HTML) Get PDF (608K)

Options for accessing this content:

  • If you have access to this content through a society membership, please first log in to your society website.
  • If you would like institutional access to this content, please recommend the title to your librarian.
  • Login via other institutional login options http://onlinelibrary.wiley.com/login-options.
  • You can purchase online access to this Article for a 24-hour period (price varies by title)
    • If you already have a Wiley Online Library or Wiley InterScience user account: login above and proceed to purchase the article.
    • New Users: Please register, then proceed to purchase the article.

If your institution is a registered Wiley Online Library customer, you can log in under your institution's name to see our content. This access is provided by Shibboleth or Athens.

Type your institution's name in the box below. If your institution is a Wiley customer, it will appear in the list of suggested institutions.

Please register to:

  • Save publications, articles and searches
  • Get email alerts
  • Get all the benefits mentioned below!

Register now >

View Full Article with Supporting Information (HTML) Get PDF (608K)