Multiple sclerosis and viruses

Authors

  • Michel Brahic MD, PhD

    Corresponding author
    1. Department of Microbiology Immunology, Stanford University School of Medicine, Stanford, CA
    • Department of Microbiology Immunology, Stanford University School of Medicine, 299 Campus Drive, Stanford, CA 94305
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Abstract

Discussing the problem of multiple sclerosis and viruses should not be limited to reviewing the epidemiological evidence in favor, or against, a particular candidate, such as Epstein-Barr virus or human herpes virus 6. In this text, I discuss the difficulty of going from association to causation in human epidemiology; the fact that viruses can trigger or prevent autoimmunity; the problem of our very limited knowledge of the viruses that we harbor as part of our metagenome; and the role of such viral flora in multifactorial diseases and also, possibly, in health. ANN NEUROL 2010;68:6–8

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