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Additional supporting information can be found in the online version of this article.

FilenameFormatSizeDescription
ANA_22277_sm_suppinfofig1a.tif288KSupplemental Figure 1: Average paths of 10 year change in global cognition and episodic memory for typical persons for CR1 (rs6656401) using the genotypic model. a. Global Cognition (AA vs GG p=0.0.520, AG vs GG p=0.0002)
ANA_22277_sm_suppinfofig1b.tif284KSupplemental Figure 1: Average paths of 10 year change in global cognition and episodic memory for typical persons for CR1 (rs6656401) using the genotypic model. b. Episodic Memory (AA vs GG p=0.0.666, AG vs GG p=0.001)
ANA_22277_sm_suppinfofig2a.tif312KSupplemental Figure 2: Average paths of 10 year change in global cognition and episodic memory for typical persons for CR1 (rs6656401) using the dominant model, stratified by study. a. Global Cognition, (MAP p=0.055, ROS p=0.028)
ANA_22277_sm_suppinfofig2b.tif304KSupplemental Figure 2: Average paths of 10 year change in global cognition and episodic memory for typical persons for CR1 (rs6656401) using the dominant model, stratified by study. b. Episodic Memory, (MAP p=0.028, ROS p=0.141)
ANA_22277_sm_suppinfotab.doc141KSupplementary Table 1 Relationship between genes and change in global cognition over time stratified by study.

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