Measurement of intraocular and intracranial pressure: Is there a relationship?
Article first published online: 27 JUN 2011
Copyright © 2011 American Neurological Association
Annals of Neurology
Volume 70, Issue 2, pages 323–326, August 2011
How to Cite
Kirk, T., Jones, K., Miller, S. and Corbett, J. (2011), Measurement of intraocular and intracranial pressure: Is there a relationship?. Ann Neurol., 70: 323–326. doi: 10.1002/ana.22414
- Issue published online: 5 AUG 2011
- Article first published online: 27 JUN 2011
- Accepted manuscript online: 7 MAR 2011 10:40AM EST
- Manuscript Accepted: 25 FEB 2011
- Manuscript Revised: 21 FEB 2011
- Manuscript Received: 6 AUG 2010
To study whether noninvasive, intraocular pressure (IOP) measurements significantly correlate with standard intracranial pressure (ICP) measurements.
This prospective, blinded study enrolled 46 patients who were undergoing medically indicated lumbar puncture (LP). IOP was measured by applanation tonometry immediately prior to measuring LP opening pressure. One patient was excluded due to unsuccessful ICP measurement.
In the 45 patients to successfully undergo IOP and ICP measurement, there was no significant relationship between ICP and average IOP for both eyes (r = −0.005). There was no significant relationship between ICP and IOP in either eye, when studied individually(r = 0.03 ocular dexter [OD], r = −0.05 ocular sinister [OS]). There was no significant relationship between ICP and IOP when the eye best correlated to the patient's ICP was chosen (r = −0.01).
No significant relationship between ICP and IOP was observed. Noninvasive IOP measurements do not predict ICP.ANN NEUROL 2011;