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Current concepts and management of glioblastoma

  1. Matthias Preusser MD1,
  2. Sandrine de Ribaupierre MD2,
  3. Adelheid Wöhrer MD3,
  4. Sara C. Erridge MD4,
  5. Monika Hegi PhD5,
  6. Michael Weller MD6,
  7. Roger Stupp MD5,7,*

Article first published online: 22 JUL 2011

DOI: 10.1002/ana.22425

Issue

Annals of Neurology

Annals of Neurology

Volume 70, Issue 1, pages 9–21, July 2011

Additional Information

How to Cite

Preusser, M., de Ribaupierre, S., Wöhrer, A., Erridge, S. C., Hegi, M., Weller, M. and Stupp, R. (2011), Current concepts and management of glioblastoma. Ann Neurol., 70: 9–21. doi: 10.1002/ana.22425

Author Information

  1. 1

    Department of Medicine I/Oncology, Comprehensive Cancer Center Central Nervous System Tumors Unit, Medical University of Vienna, Vienna, Austria

  2. 2

    Department of Clinical Neurological Sciences, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada

  3. 3

    Institute of Neurology, Comprehensive Cancer Center Central Nervous System Tumors Unit, Medical University of Vienna, Vienna, Austria

  4. 4

    Edinburgh Cancer Centre, University of Edinburgh, Edinburgh, United Kingdom

  5. 5

    Department of Neurosurgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

  6. 6

    Department of Neurology, University Hospital Zurich, Zurich, Switzerland

  7. 7

    Department of Oncology/Hematology Riveria Chablais, Vevey, Switzerland

*Department of Neurosurgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Rue du Bugnon 46, CH-1011 Lausanne, Switzerland

Publication History

  1. Issue published online: 22 JUL 2011
  2. Article first published online: 22 JUL 2011
  3. Accepted manuscript online: 21 MAR 2011 11:19AM EST
  4. Manuscript Accepted: 11 MAR 2011
  5. Manuscript Revised: 10 MAR 2011
  6. Manuscript Received: 23 JAN 2011

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Abstract

Glioblastoma is the most common malignant primary brain tumor in adults. Its often rapid clinical course, with many medical and psychosocial challenges, requires a multidisciplinary management. Modern multimodality treatment and care improve patients' life expectancy and quality of life. This review covers major aspects of care of glioblastoma patients with a focus on the management of common symptoms and complications. We aim to provide a guide for clinicians confronted with glioblastoma patients in their everyday practice. Ann Neurol 2011;

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