Botulinum toxin-A improves the rigidity of progressive supranuclear palsy

Authors

  • Kathleen B. Polo MD,

    1. Neurology Service, Walter Reed Army Medical Center, Washington, DC
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  • Dr. Bahman Jabbari MD

    Corresponding author
    1. Neurology Service, Walter Reed Army Medical Center, Washington, DC
    2. Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda MD
    • Neurology Service, Walter Reed Army Medical Center, Washington DC 20307
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Abstract

Botulinum toxin-A (botox) can improve spasticity and decrease painful spasms in the affected limbs of patients with multiple sclerosis. We report significant improvement of muscle rigidity in the upper limbs after focal administration of botulinum toxin A to 2 patients with progressive supranuclear palsy.

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