Annals of Neurology

Cover image for Vol. 68 Issue 4

October 2010

Volume 68, Issue 4

Pages A6–A13, 415–566

  1. Message from the Editor

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Malignant middle cerebral artery stroke: Where ischemia meets the scalpel (pages A6–A8)

      S. Andrew Josephson, Stephen L. Hauser and S. Claiborne Johnston

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22265

  2. NerveCenter

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
  3. Discoveries in Neuroscience

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
  4. Editorial

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
  5. Editorials

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Meningeal gyrations (pages 421–423)

      Jim Barkovich and Robert F. Hevner

      Version of Record online: 23 SEP 2010 | DOI: 10.1002/ana.22140

  6. Neurological Progress

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Mesial temporal lobe epilepsy: How do we improve surgical outcome? (pages 424–434)

      Maria Thom, Gary W. Mathern, J. Helen Cross and Edward H. Bertram

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22142

  7. Original Articles

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Prediction of malignant middle cerebral artery infarction by magnetic resonance imaging within 6 hours of symptom onset: A prospective multicenter observational study (pages 435–445)

      Götz Thomalla, Frank Hartmann, Eric Juettler, Oliver C. Singer, Fritz-Georg Lehnhardt, Martin Köhrmann, Jan F. Kersten, Anna Krützelmann, Marek C. Humpich, Jan Sobesky, Christian Gerloff, Arno Villringer, Jens Fiehler, Tobias Neumann-Haefelin, Peter D. Schellinger, Joachim Röther and for the Clinical Trial Net of the German Competence Network Stroke

      Version of Record online: 23 SEP 2010 | DOI: 10.1002/ana.22125

    2. Amyloid and tau proteins in cortical brain biopsy and Alzheimer's disease (pages 446–453)

      Ville Leinonen, Anne M. Koivisto, Sakari Savolainen, Jaana Rummukainen, Juuso N. Tamminen, Tomi Tillgren, Sannakaisa Vainikka, Okko T. Pyykkö, Juhani Mölsä, Mikael Fraunberg, Tuula Pirttilä, Juha E. Jääskeläinen, Hilkka Soininen, Jaakko Rinne and Irina Alafuzoff

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22100

    3. Primary cellular meningeal defects cause neocortical dysplasia and dyslamination (pages 454–464)

      Jonathan H. Hecht, Julie A. Siegenthaler, Katelin P. Patterson and Samuel J. Pleasure

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22103

  8. Original Article

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords (pages 465–476)

      Géraldine Androdias, Richard Reynolds, Marie Chanal, Cécile Ritleng, Christian Confavreux and Serge Nataf

      Version of Record online: 4 AUG 2010 | DOI: 10.1002/ana.22054

  9. Original Articles

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis (pages 477–493)

      Roberta Magliozzi, Owain W. Howell, Cheryl Reeves, Federico Roncaroli, Richard Nicholas, Barbara Serafini, Francesca Aloisi and Richard Reynolds

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22230

  10. Rapid Communication

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. A phase 3 trial of extended release oral dalfampridine in multiple sclerosis (pages 494–502)

      Andrew D. Goodman, Theodore R. Brown, Keith R. Edwards, Lauren B. Krupp, Randall T Schapiro, Ron Cohen, Lawrence N. Marinucci, Andrew R. Blight and on behalf of the MSF204 Investigators

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22240

    2. B-vitamins reduce the long-term risk of depression after stroke: The VITATOPS-DEP trial (pages 503–510)

      Osvaldo P. Almeida, Kylie Marsh, Helman Alfonso, Leon Flicker, Timothy M.E. Davis and Graeme J. Hankey

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22189

  11. Original Articles

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Early onset collagen VI myopathies: Genetic and clinical correlations (pages 511–520)

      Laura Briñas, Pascale Richard, Susana Quijano-Roy, Corine Gartioux, Céline Ledeuil, Emmanuelle Lacène, Samira Makri, Ana Ferreiro, Svetlana Maugenre, Haluk Topaloglu, Göknur Haliloglu, Isabelle Pénisson-Besnier, Pierre-Yves Jeannet, Luciano Merlini, Carmen Navarro, Annick Toutain, Denys Chaigne, Isabelle Desguerre, Christine de Die-Smulders, Murielle Dunand, Bernard Echenne, Bruno Eymard, Thierry Kuntzer, Kim Maincent, Michèle Mayer, Ghislaine Plessis, François Rivier, Filip Roelens, Tanya Stojkovic, Ana Lía Taratuto, Fabiana Lubieniecki, Soledad Monges, Christine Tranchant, Louis Viollet, Norma B. Romero, Brigitte Estournet, Pascale Guicheney and Valérie Allamand

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22087

    2. A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease (pages 521–534)

      Adrian W. Laxton, David F. Tang-Wai, Mary Pat McAndrews, Dominik Zumsteg, Richard Wennberg, Ron Keren, John Wherrett, Gary Naglie, Clement Hamani, Gwenn S. Smith and Andres M. Lozano

      Version of Record online: 4 AUG 2010 | DOI: 10.1002/ana.22089

  12. Brief Communication

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Lack of shunt response in suspected idiopathic normal pressure hydrocephalus with Alzheimer disease pathology (pages 535–540)

      Roy Hamilton, Sunil Patel, Edward B. Lee, Eric M. Jackson, Joanna Lopinto, Steven E. Arnold, Christopher M. Clark, Anuj Basil, Leslie M. Shaw, Sharon X. Xie, M. Sean Grady and John Q. Trojanowski

      Version of Record online: 8 MAR 2010 | DOI: 10.1002/ana.22015

    2. Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosis (pages 540–545)

      Peter J. Darlington, Marie-Noëlle Boivin, Christel Renoux, Moïra François, Jacques Galipeau, Mark S. Freedman, Harold L. Atkins, Jeffrey A. Cohen, Luis Solchaga and Amit- Bar-Or

      Version of Record online: 26 JUL 2010 | DOI: 10.1002/ana.22065

  13. Brief Communications

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy (pages 545–548)

      Gregory A. Dierksen, Maureen E. Skehan, Muhammad A. Khan, Jed Jeng, R.N. Kaveer Nandigam, John A. Becker, Ashok Kumar, Krista L. Neal, Rebecca A. Betensky, Matthew P. Frosch, Jonathan Rosand, Keith A. Johnson, Anand Viswanathan, David H. Salat and Steven M. Greenberg

      Version of Record online: 23 SEP 2010 | DOI: 10.1002/ana.22099

    2. Direct interaction between causative genes of DYT1 and DYT6 primary dystonia (pages 549–553)

      Sophie Gavarini, Corinne Cayrol, Tania Fuchs, Natalia Lyons, Michelle E. Ehrlich, Jean-Philippe Girard and Laurie J. Ozelius

      Version of Record online: 23 SEP 2010 | DOI: 10.1002/ana.22138

  14. Brief Communication

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. The dystonia gene DYT1 is repressed by the transcription factor THAP1 (DYT6) (pages 554–559)

      Frank J. Kaiser, Alma Osmanoric, Aleksandar Rakovic, Alev Erogullari, Nils Uflacker, Diana Braunholz, Thora Lohnau, Slobodanka Orolicki, Melanie Albrecht, Gabriele Gillessen-Kaesbach, Christine Klein and Katja Lohmann

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22157

  15. Letter to the Editor

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Reply (pages 561–562)

      Florian Doepp, Friedemann Paul, José M. Valdueza, Klaus Schmierer and Stephan J. Schreiber

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22181

    2. Reply (pages 563–564)

      Omar Khan, Massimo Filippi, Mark S. Freedman, Frederik Barkhof, Paula Dore-Duffy, Hans Lassman, Bruce Trapp, Amit Bar-Or, Imad Zak, Marilyn J Siegel and Robert Lisak

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22145

  16. Letters

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Is arginine test a reliable tool for differential diagnosis of multiple system atrophy? (pages 564–565)

      Maria Teresa Pellecchia, Rosario Pivonello, Annamaria Colao and Paolo Barone

      Version of Record online: 23 SEP 2010 | DOI: 10.1002/ana.22148

  17. Letter to the Editor

    1. Top of page
    2. Message from the Editor
    3. NerveCenter
    4. Discoveries in Neuroscience
    5. Editorial
    6. Editorials
    7. Neurological Progress
    8. Original Articles
    9. Original Article
    10. Original Articles
    11. Rapid Communication
    12. Original Articles
    13. Brief Communication
    14. Brief Communications
    15. Brief Communication
    16. Letter to the Editor
    17. Letters
    18. Letter to the Editor
    1. Reply (pages 565–566)

      Raquel C. Gardner and Jeremy D. Schmahmann

      Version of Record online: 25 OCT 2010 | DOI: 10.1002/ana.22147

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