The authors thank Dr. Terrence R. Burke, Jr. (NCI, NIH) for reading the manuscript and valuable discussions. We also thank Ms. Akane Omagari, Ms. Kiyomi Hashimoto, and Mr. Akira Matsumura for technical assistance in the preparation of cyclic peptides. This work was supported by Health and Labour Sciences Research Grants (Research on HIV/AIDS) and a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan. Computation time was provided by the Supercomputer Laboratory, Institute for Chemical Research, Kyoto University. S.O. is grateful for a Research Fellowship from the Japan Society for the Promotion of Science for Young Scientists.
Molecular-Size Reduction of a Potent CXCR4-Chemokine Antagonist Using Orthogonal Combination of Conformation- and Sequence-Based Libraries†
Article first published online: 16 JUL 2003
Copyright © 2003 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 115, Issue 28, pages 3373–3375, July 21, 2003
How to Cite
Fujii, N., Oishi, S., Hiramatsu, K., Araki, T., Ueda, S., Tamamura, H., Otaka, A., Kusano, S., Terakubo, S., Nakashima, H., Broach, J. A., Trent, J. O., Wang, Z.-x. and Peiper, S. C. (2003), Molecular-Size Reduction of a Potent CXCR4-Chemokine Antagonist Using Orthogonal Combination of Conformation- and Sequence-Based Libraries. Angew. Chem., 115: 3373–3375. doi: 10.1002/ange.200351024
- Issue published online: 16 JUL 2003
- Article first published online: 16 JUL 2003
- Manuscript Received: 27 JAN 2003
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