Get access

New Reactions of IBX: Oxidation of Nitrogen- and Sulfur-Containing Substrates To Afford Useful Synthetic Intermediates

Authors

  • K. C. Nicolaou Prof. Dr.,

    1. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2469
    2. Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Search for more papers by this author
  • Casey J. N. Mathison,

    1. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2469
    2. Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Search for more papers by this author
  • Tamsyn Montagnon Dr.

    1. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA, Fax: (+1) 858-784-2469
    2. Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Search for more papers by this author

  • We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. Financial support for this work was provided by the National Institutes of Health (USA) and the Skaggs Institute for Chemical Biology.

Abstract

original image

Neu in der Werkzeugkiste: Die Verwendung von 2-Iodoxybenzoesäure (IBX) ermöglicht die Herstellung einer Vielfalt synthetisch nützlicher Zwischenstufen. Unter anderem lassen sich Amine zu Iminen, Dithiane zu Carbonylgruppen, N-Heterocyclen zu N-Heteroarenen und Hydroxylamine zu Oximen in hohen Ausbeuten umsetzen.

Get access to the full text of this article

Ancillary