Block-Selected Molecular Recognition and Formation of Polypseudorotaxanes between Poly(propylene oxide)-Poly(ethylene oxide)-Poly(propylene oxide) Triblock Copolymers and α-Cyclodextrin

Authors

  • Jun Li Dr.,

    1. Molecular and Bio-Materials Cluster Institute of Materials Research and Engineering (IMRE) 3 Research Link, Singapore 117602 (Republic of Singapore) Fax: (+65) 6872-0785
    2. Division of Bioengineering Faculty of Engineering, National University of Singapore Singapore 117576 (Republic of Singapore)
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  • Xiping Ni,

    1. Molecular and Bio-Materials Cluster Institute of Materials Research and Engineering (IMRE) 3 Research Link, Singapore 117602 (Republic of Singapore) Fax: (+65) 6872-0785
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  • Kam Leong Prof.

    1. Molecular and Bio-Materials Cluster Institute of Materials Research and Engineering (IMRE) 3 Research Link, Singapore 117602 (Republic of Singapore) Fax: (+65) 6872-0785
    2. Department of Biomedical Engineering Johns Hopkins University Baltimore, MD 21205, USA
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  • This work was financially support by A*STAR (Agency of Science, Technology, and Research, Singapore). The authors thank Mr. Z. Zhou and Mr. B. Chen for NMR and X-ray diffraction measurements, respectively.

Abstract

original image

Bisher galt eine Poly(propylenoxid)-Kette (PPO) als unüberwindbar für α-Cyclodextrin, doch kann der mittlere Poly(ethylenoxid)-Block (PPE) von PPO-PEO-PPO-Triblock-Copolymeren selektiv von α-Cyclodextrin erkannt und eingeschlossen werden. Hierbei entstehen Polypseudorotaxane (siehe Schema) – auch wenn PEO von zwei PPOs flankiert ist.

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