Fluorescent Probes for Hydrogen Peroxide Based on a Non-Oxidative Mechanism

Authors

  • Hatsuo Maeda Prof.,

    1. Division of Analytical Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, 1–6 Yamada-oka, Suita, Osaka, 565–0871, Japan, Fax: (+81) 668-798-206
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  • Yuka Fukuyasu,

    1. Division of Analytical Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, 1–6 Yamada-oka, Suita, Osaka, 565–0871, Japan, Fax: (+81) 668-798-206
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  • Shoko Yoshida,

    1. Division of Analytical Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, 1–6 Yamada-oka, Suita, Osaka, 565–0871, Japan, Fax: (+81) 668-798-206
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  • Masako Fukuda,

    1. Division of Analytical Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, 1–6 Yamada-oka, Suita, Osaka, 565–0871, Japan, Fax: (+81) 668-798-206
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  • Kanako Saeki,

    1. Division of Analytical Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, 1–6 Yamada-oka, Suita, Osaka, 565–0871, Japan, Fax: (+81) 668-798-206
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  • Hiromi Matsuno,

    1. Division of Analytical Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, 1–6 Yamada-oka, Suita, Osaka, 565–0871, Japan, Fax: (+81) 668-798-206
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  • Yuji Yamauchi Dr.,

    1. Division of Analytical Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, 1–6 Yamada-oka, Suita, Osaka, 565–0871, Japan, Fax: (+81) 668-798-206
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  • Kenji Yoshida,

    1. Division of Environmental Bioengineering, Graduate School of Pharmaceutical Sciences, Osaka University, Japan
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  • Kazumasa Hirata Dr.,

    1. Division of Environmental Bioengineering, Graduate School of Pharmaceutical Sciences, Osaka University, Japan
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  • Kazuhisa Miyamoto Prof.

    1. Division of Environmental Bioengineering, Graduate School of Pharmaceutical Sciences, Osaka University, Japan
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  • This work was supported in part by research grants from the Shimadzu Science Foundation, the Suntory Institute for Bioorganic Research, and the Mochida Memorial Foundation for Medical and Pharmaceutical Research, as well as by a Grant-in-Aid for Scientific Research (B) (15390012) from the Ministry of Education, Science, Sports, and Culture of Japan.

Abstract

original image

Die hochselektive Detektion von H2O2 beruht auf der Desulfonylierung von 1 zum Fluorescein-Derivat nach einem nichtoxidativen Mechanismus. Mit dieser Methode wurde die Bildung von H2O2 in Algenzellen untersucht; dabei kamen Acetylderivate von 1 als Fluoreszenzsonden zum Einsatz.

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