This work was supported by the National Institutes of Health (NIH) Grants GM068011 and DK51788 (to R.M.W. and M.T.C.R, respectively) and the National Science Foundation Grant CHE0202827 (to R.M.W). The Cell Culture Core of the USC Center for Liver Disease (P30 DK 48522) provided the rat hepatocytes used in these studies. We are grateful to Array Biopharma for fellowship support to R.E.L. We thank Dr. A. Humpage of the Australian Water Quality Center, South Australia for providing a sample of natural 7-deoxycylidrospermopsin; Dr. G. Shaw for providing a spectra of 5; and Dr. C. Rithner for helpful discussions concerning the NMR analysis.
Synthesis of the Putative Structure of 7-Deoxycylindrospermopsin: C7 Oxygenation Is Not Required for the Inhibition of Protein Synthesis†
Article first published online: 18 MAY 2005
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 117, Issue 25, pages 3947–3949, June 20, 2005
How to Cite
Looper, R. E., Runnegar, M. T. C. and Williams, R. M. (2005), Synthesis of the Putative Structure of 7-Deoxycylindrospermopsin: C7 Oxygenation Is Not Required for the Inhibition of Protein Synthesis. Angew. Chem., 117: 3947–3949. doi: 10.1002/ange.200500520
- Issue published online: 10 JUN 2005
- Article first published online: 18 MAY 2005
- Manuscript Received: 11 FEB 2005
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