Construction of Pseudo-Heterochiral and Homochiral Di-μ-oxotitanium(Schiff base) Dimers and Enantioselective Epoxidation Using Aqueous Hydrogen Peroxide

Authors

  • Kazuhiro Matsumoto,

    1. Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan, Fax: (+81) 92-642-2607
    2. CREST, Japan Science and Technology Agency (JST), Japan
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  • Yuji Sawada,

    1. Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan, Fax: (+81) 92-642-2607
    2. CREST, Japan Science and Technology Agency (JST), Japan
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  • Bunnai Saito,

    1. Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan, Fax: (+81) 92-642-2607
    2. CREST, Japan Science and Technology Agency (JST), Japan
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  • Ken Sakai,

    1. Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan, Fax: (+81) 92-642-2607
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  • Tsutomu Katsuki

    1. Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan, Fax: (+81) 92-642-2607
    2. CREST, Japan Science and Technology Agency (JST), Japan
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Abstract

original image

Salen im Doppelpack: Die Meerwein-Ponndorf-Verley-Reduktion von [Ti(salen)(OiPr)2]-Komplexen (salen=Bis(salicyliden)ethylendiaminato) führt nach anschließender Umsetzung mit Wasser zu pseudo-heterochiralen und homochiralen Di-μ-oxo-Titandimeren. Diese Dimere, z. B. das (aR,S,Δ,aR,S,Δ)-Dimer 1, katalysieren die Epoxidierungen einfacher Olefine durch Wasserstoffperoxid in Wasser (siehe Schema) mit ee-Werten bis 99 % und Umsatzzahlen bis 4600.

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