This work was supported by the National Science and Engineering Research Council of Canada (NSERC), by the Canadian Institute of Health Research (CIHR), and by the Cancer Research Center (CRC). F.G., X.Y., and O.M.B. were supported by scholarship awards from the Chemical Biology Strategic Training Initiative of CIHR. The authors are grateful to G. D. Wright at McMaster University for sharing his AAC(6′)-Ii expression plasmid.
Regio- and Chemoselective 6′-N-Derivatization of Aminoglycosides: Bisubstrate Inhibitors as Probes To Study Aminoglycoside 6′-N-Acetyltransferases†
Version of Record online: 5 OCT 2005
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 117, Issue 42, pages 7019–7022, October 28, 2005
How to Cite
Gao, F., Yan, X., Baettig, O. M., Berghuis, A. M. and Auclair, K. (2005), Regio- and Chemoselective 6′-N-Derivatization of Aminoglycosides: Bisubstrate Inhibitors as Probes To Study Aminoglycoside 6′-N-Acetyltransferases. Angew. Chem., 117: 7019–7022. doi: 10.1002/ange.200501399
- Issue online: 25 OCT 2005
- Version of Record online: 5 OCT 2005
- Manuscript Revised: 25 JUL 2005
- Manuscript Received: 22 APR 2005
Supporting information (including experimental procedures, characterization data, some NMR spectra and HPLC traces) for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2005/z501399_s.pdf or from the author.
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