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Stimuli-Responsive Controlled-Release Delivery System Based on Mesoporous Silica Nanorods Capped with Magnetic Nanoparticles†

  1. Supratim Giri,
  2. Brian G. Trewyn,
  3. Michael P. Stellmaker,
  4. Victor S.-Y. Lin Prof. Dr.

Article first published online: 22 JUL 2005

DOI: 10.1002/ange.200501819

Issue

Angewandte Chemie

Angewandte Chemie

Volume 117, Issue 32, pages 5166–5172, August 12, 2005

Additional Information

How to Cite

Giri, S., Trewyn, B. G., Stellmaker, M. P. and Lin, V. S.-Y. (2005), Stimuli-Responsive Controlled-Release Delivery System Based on Mesoporous Silica Nanorods Capped with Magnetic Nanoparticles. Angew. Chem., 117: 5166–5172. doi: 10.1002/ange.200501819

Author Information

  1. Department of Chemistry and U.S. DOE Ames Laboratory, Iowa State University, Ames, Iowa 50011, USA, Fax: (+1) 515-294-0105

  1. †

    We thank the U.S. National Science Foundation (grant nos. CHE-0239570 and CMS-0409625) for financial support of this research.

Publication History

  1. Issue published online: 8 AUG 2005
  2. Article first published online: 22 JUL 2005
  3. Manuscript Received: 26 MAY 2005

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Keywords:

  • Fluoreszenz;
  • Magnetische Eigenschaften;
  • Mesoporöse Materialien;
  • Nanostrukturen;
  • Wirkstoff-Transport
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Halt, abliefern! Fluoresceinmoleküle, die in den Poren eines Kern-Schale-Systems aus mesoporösen Siliciumoxid-Nanostäbchen und superparamagnetischen Eisenoxid-Nanopartikeln eingeschlossen sind, werden in Gegenwart eines externen Magnetfelds freigesetzt, doch nur als Antwort auf in Zellen produzierte Antioxidantien. Das macht ein solches System für die kontrollierte Wirkstoffabgabe interessant.

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