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2-Thioindoles as Precursors to Spiro-Fused Indolines: Synthesis of (±)-Dehaloperophoramidine

Authors


  • This research was supported by NIH General Medical Sciences (GM 61608) and the University of Utah. The authors thank Dr. Atta M. Arif, Dr. Charles L. Mayne, and Elliot M. Rachlin for help with the X-ray analysis, NMR spectroscopy, and mass spectrometry, respectively. Professor Chris M. Ireland is acknowledged for providing the spectral data of dehaloperophoramidine.

Abstract

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Der Kreis schließt sich: Die Cyclisierung eines 2-Thioindols mit einem elektrophilen Substituenten ist der Schlüsselschritt einer Synthesestrategie zur Erzeugung von Indolalkaloiden der Perophoramidin- und Communesin-Klasse.

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