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Radical Alkylation of Bis(silyloxy)enamine Derivatives of Organic Nitro Compounds

Authors

  • Jin Young Lee,

    1. Center for Molecular Design & Synthesis and Department of Chemistry, School of Molecular Science, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea, Fax: (+82) 42-869-8370
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  • Young-Taek Hong,

    1. Center for Molecular Design & Synthesis and Department of Chemistry, School of Molecular Science, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea, Fax: (+82) 42-869-8370
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  • Sunggak Kim Prof. Dr.

    1. Center for Molecular Design & Synthesis and Department of Chemistry, School of Molecular Science, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea, Fax: (+82) 42-869-8370
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  • We thank the CMDS and BK21 programs for financial support.

Abstract

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Die radikalische Alkylierung in β-Stellung zu einer Nitrogruppe beginnt mit der Umwandlung einer organischen Nitroverbindung in ein Bis(silyloxy)enamin (siehe Schema; TBS=tert-Butyldimethylsilyl, Tf=Triflat). Ein weiterer Vorteil der Methode besteht darin, dass aus der Nitrogruppe eine präparativ nützliche Oximethergruppe erzeugt wird.

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