Two-Directional Annelation: Dual Benzyne Cycloadditions Starting from Bis(sulfonyloxy)diiodobenzene

Authors

  • Toshiyuki Hamura Dr.,

    1. Department of Chemistry, Tokyo Institute of Technology and SORST Japan Science and Technology Agency (JST), 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8551, Japan, Fax: (+81) 3-5734-2788
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  • Tetsu Arisawa,

    1. Department of Chemistry, Tokyo Institute of Technology and SORST Japan Science and Technology Agency (JST), 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8551, Japan, Fax: (+81) 3-5734-2788
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  • Takashi Matsumoto Dr.,

    1. Department of Chemistry, Tokyo Institute of Technology and SORST Japan Science and Technology Agency (JST), 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8551, Japan, Fax: (+81) 3-5734-2788
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  • Keisuke Suzuki Prof. Dr.

    1. Department of Chemistry, Tokyo Institute of Technology and SORST Japan Science and Technology Agency (JST), 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8551, Japan, Fax: (+81) 3-5734-2788
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  • Partial financial support provided by the 21st Century COE program is gratefully acknowledged.

Abstract

original image

Links eine und rechts eine Arincycloaddition gelingt an Bis(sulfonyloxy)diiodbenzolderivaten I, einem Syntheseäquivalent von 3-Alkoxy-1,4-benzdiin II. Dabei verlaufen die Arinerzeugung durch selektiven Halogen-Lithium-Austausch in I und die Cycloadditionen mit den beiden Arinophilen 1 und 2 als Tandemreaktionen, sodass hoch funktionalisierte Bis-Cycloaddukte schnell zugänglich sind.

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