In Vitro and Intracellular Production of Peptide-Encapsulated Fluorescent Silver Nanoclusters

Authors

  • Junhua Yu Dr.,

    1. School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332-0400, USA, Fax: (+1) 404-894-7452
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  • Sandeep A. Patel,

    1. School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332-0400, USA, Fax: (+1) 404-894-7452
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  • Robert M. Dickson Prof.

    1. School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332-0400, USA, Fax: (+1) 404-894-7452
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  • The authors gratefully acknowledge financial support from NSF BES-0323453, Invitrogen Corp., NIH R01M68732, and NIH P20072021, and thank Prof. D. F. Doyle for use of his cell-culture facility, and Prof. Y.-L. Tzeng for the gift of the peptides.

Abstract

original image

Nucleoli mit Silberstreifen: Die Bildung von Silbernanoclustern durch Fluoreszenz-Photoaktivierung wurde für das Anfärben von Zellen bei niedriger Silbernitratkonzentration und Raumtemperatur genutzt. Das Bild zeigt Bildung und Zerfall von in Peptiden eingeschlossenen Silbernanoclustern in NIH 3T3-Zellen.

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