M. Reese and Dr. V. M. Sánchez-Pedregal contributed equally to this work.
Structural Basis of the Activity of the Microtubule-Stabilizing Agent Epothilone A Studied by NMR Spectroscopy in Solution†
Article first published online: 2 FEB 2007
Copyright © 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 119, Issue 11, pages 1896–1900, March 5, 2007
How to Cite
Reese, M., Sánchez-Pedregal, Víctor M., Kubicek, K., Meiler, J., Blommers, Marcel J. J., Griesinger, C. and Carlomagno, T. (2007), Structural Basis of the Activity of the Microtubule-Stabilizing Agent Epothilone A Studied by NMR Spectroscopy in Solution. Angew. Chem., 119: 1896–1900. doi: 10.1002/ange.200604505
This work was supported by the Max-Planck-Gesellschaft, the Volkswagenstiftung (grant no. I/80 798 to T.C.), by the European Union (Marie Curie fellowship to V.M.S.-P.), and by the DAAD (postdoctoral fellowship PKZ A/06/04203 to K.K.). Computer time was obtained from the GWDG (Göttingen), the RZG (Garching), and the NIC (Jülich). We thank O. Haan for support in the matrix calculations, and U. Schwardmann and C. Boehme for continuous technical help. We especially thank H. Stark for the electron microscopy images.
- Issue published online: 26 FEB 2007
- Article first published online: 2 FEB 2007
- Manuscript Received: 3 NOV 2006
- Volkswagenstiftung. Grant Number: I/80 798
- European Union
- DAAD. Grant Number: PKZ A/06/04203
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