Zuschrift

A Pocket-Sized Convective PCR Thermocycler†

  1. Nitin Agrawal Dr.1,3,
  2. Yassin A. Hassan Prof.2,
  3. Victor M. Ugaz Prof.1

Article first published online: 30 APR 2007

DOI: 10.1002/ange.200700306

Issue

Angewandte Chemie

Angewandte Chemie

Volume 119, Issue 23, pages 4394–4397, June 4, 2007

Additional Information

How to Cite

Agrawal, N., Hassan, Yassin A. and Ugaz, Victor M. (2007), A Pocket-Sized Convective PCR Thermocycler. Angew. Chem., 119: 4394–4397. doi: 10.1002/ange.200700306

Author Information

  1. 1

    Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX 77843, USA, Fax: (+1) 979-458-1002

  2. 2

    Department of Nuclear Engineering, Texas A&M University, College Station, TX 77843, USA

  3. 3

    Present address: Center for Engineering in Medicine/Department of Surgery, Massachusetts General Hospital, Shriners Burns Hospital and Harvard Medical School, Boston, MA 02114, USA

  1. †

    This work was supported by the National Institutes of Health under grants K22-HG02297 and R01-HG003364. We thank Prof. Mihir Sen for helpful discussions regarding modeling the convective flow. We are also grateful to Ling Zhen for assistance with computational-flow simulations.

Publication History

  1. Issue published online: 24 MAY 2007
  2. Article first published online: 30 APR 2007
  3. Manuscript Received: 23 JAN 2007

Funded by

  • National Institutes of Health. Grant Numbers: K22-HG02297, R01-HG003364

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Keywords:

  • Analytische Methoden;
  • DNA‒Replikation;
  • Mikroreaktoren;
  • Molekularbiologie;
  • Polymerasekettenreaktion
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Taschen-PCR: Ein innovativer Thermocycler nutzt die natürliche Konvektion, um langkettige und Multiplex-DNA schnell durch Polymerasekettenreaktion (PCR) zu vervielfältigen. Der einfache Aufbau benötigt ein Minimum an elektrischer Leistung und kann daher in einem batteriebetriebenen Tascheninstrument mit Produktionskosten um 10 US$ umgesetzt werden.

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