Get access

A Two-Photon Fluorescent Probe for Calcium Waves in Living Tissue

Authors

  • Hwan Myung Kim,

    1. Department of Chemistry and Center for Electro- and Photoresponsive Molecules, Korea University, 1-Anamdong, Seoul, 136-701, Korea, Fax: (+82) 2-3290-3544
    Search for more papers by this author
  • Bo Ra Kim,

    1. Department of Chemistry and Center for Electro- and Photoresponsive Molecules, Korea University, 1-Anamdong, Seoul, 136-701, Korea, Fax: (+82) 2-3290-3544
    Search for more papers by this author
  • Jin Hee Hong Dr.,

    1. National Creative Research Initiative Center for Neurodynamics and Department of Physics, Korea University, 1-Anamdong, Seoul, 136-701, Korea
    Search for more papers by this author
  • Jin-Sung Park Dr.,

    1. National Creative Research Initiative Center for Neurodynamics and Department of Physics, Korea University, 1-Anamdong, Seoul, 136-701, Korea
    Search for more papers by this author
  • Kyoung J. Lee Prof. Dr.,

    1. National Creative Research Initiative Center for Neurodynamics and Department of Physics, Korea University, 1-Anamdong, Seoul, 136-701, Korea
    Search for more papers by this author
  • Bong Rae Cho Prof. Dr.

    1. Department of Chemistry and Center for Electro- and Photoresponsive Molecules, Korea University, 1-Anamdong, Seoul, 136-701, Korea, Fax: (+82) 2-3290-3544
    Search for more papers by this author

  • This work was supported by KRF-2004-201-C00067. J.H.H. and K.J.L. were supported by Creative Research Initiatives of the Korean Ministry of Science and Technology.

Abstract

original image

Intrazelluläre Signalgebung: Die neuartige Zweiphotonen-Fluoreszenzsonde ACa1 kann Calciumwellen in Zellen und lebendem Gewebe über lange Zeit und ohne Probleme durch „Fehlschüsse“ sichtbar machen (siehe Bild). Die Sonde zeichnet die Calciumwellen in einer Tiefe von etwa 150 μm in lebenden Geweben über mehr als 1100 s und ohne Störung durch Photobleichen auf.

Get access to the full text of this article

Ancillary