Asymmetric Simmons–Smith Reaction of Allylic Alcohols with Al Lewis Acid/N Lewis Base Bifunctional Al(Salalen) Catalyst


  • This study was supported by Grant-in-Aid for Scientific Research (Specially Promoted Research 18002011) and the Global COE Program (Science for Future Molecular Systems) from the Ministry of Education, Science, and Culture (Japan). salalen= salen/salan hybrid; salen=N,N′-bis(salicylidene)ethylenediamine); salan=N,N′-bis(o-hydroxybenzyl)-1,2-diaminoethane.


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Schonend zum Dreiring: Hoch enantioselektive Simmons-Smith-Reaktionen mit trans-disubstituierten Allylalkoholen gelingen bei Raumtemperatur in Gegenwart katalytischer Mengen eines Aluminium-Salalen-Komplexes (siehe Schema).