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Synthesis of 1,9-Dideoxy-pre-axinellamine

Authors

  • Junichiro Yamaguchi Dr.,

    1. Department of Chemistry, The Scripps Research Institute, 10650 North Torrey Pines Road, La Jolla, CA, 92037, USA, Fax: (+1) 858-784-7375
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    • Both authors contributed equally to this paper.

  • Ian B. Seiple,

    1. Department of Chemistry, The Scripps Research Institute, 10650 North Torrey Pines Road, La Jolla, CA, 92037, USA, Fax: (+1) 858-784-7375
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    • Both authors contributed equally to this paper.

  • Ian S. Young Dr.,

    1. Department of Chemistry, The Scripps Research Institute, 10650 North Torrey Pines Road, La Jolla, CA, 92037, USA, Fax: (+1) 858-784-7375
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  • Daniel P. O'Malley,

    1. Department of Chemistry, The Scripps Research Institute, 10650 North Torrey Pines Road, La Jolla, CA, 92037, USA, Fax: (+1) 858-784-7375
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  • Michael Maue Dr.,

    1. Department of Chemistry, The Scripps Research Institute, 10650 North Torrey Pines Road, La Jolla, CA, 92037, USA, Fax: (+1) 858-784-7375
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  • Phil S. Baran Prof. Dr.

    1. Department of Chemistry, The Scripps Research Institute, 10650 North Torrey Pines Road, La Jolla, CA, 92037, USA, Fax: (+1) 858-784-7375
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  • We thank Dr. Arnold Rheingold (UCSD) for X-ray crystallographic assistance. Financial support for this work was provided by the NIH/NIGMS (GM-073949), Bristol–Myers Squibb, Merck, the Japan Society for the Promotion of Science (JSPS) for a postdoctoral fellowship to J.Y., the Natural Sciences and Engineering Research Council of Canada (NSERC) for a postdoctoral fellowship to I.S.Y., the U.S. Department of Defense and the Hertz Foundation for a predoctoral fellowships to D.P.O, and the German Academic Exchange Service (DAAD) for a postdoctoral fellowship to M.M.

Abstract

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In Reichweite: Eine 19-stufige Synthese von 1,9-Didesoxypräaxinellamin wurde entworfen und ausgeführt. Diese Schlüsselverbindung ist eine hypothetische Vorstufe einer ganzen Familie von Alkaloid-Naturstoffen.

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