Get access

Enantioselective Synthesis of P-Stereogenic Alkynylphosphine Oxides by Rh-Catalyzed [2+2+2] Cycloaddition

Authors

  • Goushi Nishida,

    1. Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan, Fax: (+81) 42-388-7037
    Search for more papers by this author
  • Keiichi Noguchi Prof. Dr.,

    1. Instrumentation Analysis Center, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan
    Search for more papers by this author
  • Masao Hirano Dr.,

    1. Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan, Fax: (+81) 42-388-7037
    Search for more papers by this author
  • Ken Tanaka Prof. Dr.

    1. Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan, Fax: (+81) 42-388-7037
    Search for more papers by this author

  • This work was supported partly by a Grant-in-Aid for Scientific Research (No. 19350046 and No. 19008995) from the Ministry of Education, Culture, Sports, Science, and Technology (Japan). We thank Takasago International Corporation for the gift of modified-binap ligands.

Abstract

original image

Drei mal zwei: Eine enantioselektive Synthese von P-stereogenen Alkinylphosphinoxiden verläuft über eine [2+2+2]-Cycloaddition symmetrischer Dialkinylphosphinoxide mit 1,6-Diinen (siehe Schema; Z=CH2, O oder N-Sulfonamid), wobei kationische Rhodium(I)-Komplexe von modifizierten Binap-Liganden als Katalysatoren wirken. Mit der Methode sind auch C2-symmetrische P-stereogene Bis(alkinylphosphinoxide) zugänglich.

Get access to the full text of this article

Ancillary