This work was supported by a grant from the National Institutes of Health (grant no.: CA127622 to B.S.M.). A.S.E. is a Tularik postdoctoral fellow of the Life Sciences Research Foundation. We thank M. Onega and D. O'Hagan (University of St. Andrews, UK) for kindly providing 5′-fluoro-5′-deoxyadenosine and 5-fluoro-5-deoxyribose and J. Haerle, S. Kelly, and J. Kalaitzis (University of California at San Diego, USA) for technical help with fermentation, cytotoxicity assays, and NMR analysis, respectively.
Mutasynthesis of Fluorosalinosporamide, a Potent and Reversible Inhibitor of the Proteasome†
Version of Record online: 14 APR 2008
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 120, Issue 21, pages 4000–4002, May 13, 2008
How to Cite
Eustáquio, Alessandra S. and Moore, Bradley S. (2008), Mutasynthesis of Fluorosalinosporamide, a Potent and Reversible Inhibitor of the Proteasome. Angew. Chem., 120: 4000–4002. doi: 10.1002/ange.200800177
- Issue online: 6 MAY 2008
- Version of Record online: 14 APR 2008
- Manuscript Received: 14 JAN 2008
- National Institutes of Health. Grant Number: CA127622
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