We thank the National Institutes of Health (GM 033049) and the National Science Foundation for their generous support of our programs. T.Z. thanks Novartis for a graduate fellowship. Mass spectra were provided, in part, by the Mass Spectrometry Regional Center of the University of California, San Francisco. Palladium salts were generously supplied by Johnson-Matthey. We are indebted to Dr. Kiran Guthikonda, David N. Zalatan, and Prof. Justin Du Bois for valuable discussions and donation of chemicals for the aziridination step. We thank Gilead Sciences for a reference sample of Tamiflu.
A Concise Synthesis of (−)-Oseltamivir†
Article first published online: 10 APR 2008
Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 120, Issue 20, pages 3819–3821, May 5, 2008
How to Cite
Trost, Barry M. and Zhang, T. (2008), A Concise Synthesis of (−)-Oseltamivir. Angew. Chem., 120: 3819–3821. doi: 10.1002/ange.200800282
- Issue published online: 28 APR 2008
- Article first published online: 10 APR 2008
- Manuscript Received: 19 JAN 2008
- National Institutes of Health. Grant Number: GM 033049
- National Science Foundation
- Gilead Sciences
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