Iron-Mediated Direct Arylation of Unactivated Arenes

Authors

  • Jun Wen,

    1. Department of Chemistry, Key Laboratory of Green Chemistry and Technology (Ministry of Education), Sichuan University, Chengdu, 610064 (P. R. China)
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  • Ji Zhang Dr.,

    1. Department of Chemistry, Key Laboratory of Green Chemistry and Technology (Ministry of Education), Sichuan University, Chengdu, 610064 (P. R. China)
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  • Shan-Yong Chen,

    1. Department of Chemistry, Key Laboratory of Green Chemistry and Technology (Ministry of Education), Sichuan University, Chengdu, 610064 (P. R. China)
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  • Jing Li,

    1. Department of Chemistry, Key Laboratory of Green Chemistry and Technology (Ministry of Education), Sichuan University, Chengdu, 610064 (P. R. China)
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  • Xiao-Qi Yu Dr.

    1. Department of Chemistry, Key Laboratory of Green Chemistry and Technology (Ministry of Education), Sichuan University, Chengdu, 610064 (P. R. China)
    2. State Key Laboratory of Biotherapy, Sichuan University, Chengdu, Sichuan 610041 (P. R. China), Fax: (+86) 288-541-5886
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  • This work was financially supported by the National Science Foundation of China (Nos. 20725206, 20732004 and 20572075) and the Specialized Research Fund for the Doctoral Program of Higher Education. We also thank the Sichuan University Analytical and Testing Center for NMR spectroscopic analysis.

Abstract

original image

Preisgünstig und einfach zu handhaben ist die gezeigte eisenvermittelte Kreuzkupplung, die wenig giftige Reagentien unter C-H-Aktivierung in Biaryle überführt. Unter den optimierten Reaktionsbedingungen wurden zahlreiche substituierte Phenylboronsäuren mit einfachen nichtaktivierten Arenen umgesetzt.

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