Specificity of Watson–Crick Base Pairing on a Solid Surface Studied at the Atomic Scale

Authors

  • Roberto Otero Dr.,

    1. Interdisciplinary Nanoscience Center (iNANO), Center for DNA Nanotechnology (CDNA), and Department of Physics and Astronomy, University of Aarhus, Ny Munkegade, 8000 Aarhus C (Denmark), Fax: (+45) 8612 0740
    2. Present Address: Dep. De Física de la Materia Condensada, Universidad Autónoma de Madrid (Spain)
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    • These authors contributed equally to this work.

  • Wei Xu Dr.,

    1. Interdisciplinary Nanoscience Center (iNANO), Center for DNA Nanotechnology (CDNA), and Department of Physics and Astronomy, University of Aarhus, Ny Munkegade, 8000 Aarhus C (Denmark), Fax: (+45) 8612 0740
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    • These authors contributed equally to this work.

  • Maya Lukas Dr.,

    1. Interdisciplinary Nanoscience Center (iNANO), Center for DNA Nanotechnology (CDNA), and Department of Physics and Astronomy, University of Aarhus, Ny Munkegade, 8000 Aarhus C (Denmark), Fax: (+45) 8612 0740
    2. Present Address: Institute for Nanotechnology, Forschungszentrum Karlsruhe (Germany)
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    • These authors contributed equally to this work.

  • Ross E. A. Kelly Dr.,

    1. Department of Physics, School of Physical Sciences and Engineering, King's College London (UK)
    2. Present Address: Department of Physics and Astronomy, University College London (UK)
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    • These authors contributed equally to this work.

  • Erik Lægsgaard Prof.,

    1. Interdisciplinary Nanoscience Center (iNANO), Center for DNA Nanotechnology (CDNA), and Department of Physics and Astronomy, University of Aarhus, Ny Munkegade, 8000 Aarhus C (Denmark), Fax: (+45) 8612 0740
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  • Ivan Stensgaard Prof.,

    1. Interdisciplinary Nanoscience Center (iNANO), Center for DNA Nanotechnology (CDNA), and Department of Physics and Astronomy, University of Aarhus, Ny Munkegade, 8000 Aarhus C (Denmark), Fax: (+45) 8612 0740
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  • Jørgen Kjems Prof.,

    1. Interdisciplinary Nanoscience Center (iNANO), Center for DNA Nanotechnology (CDNA), and Department of Molecular Biology, University of Aarhus (Denmark)
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  • Lev N. Kantorovich Dr.,

    1. Department of Physics, School of Physical Sciences and Engineering, King's College London (UK)
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  • Flemming Besenbacher Prof. Dr.

    1. Interdisciplinary Nanoscience Center (iNANO), Center for DNA Nanotechnology (CDNA), and Department of Physics and Astronomy, University of Aarhus, Ny Munkegade, 8000 Aarhus C (Denmark), Fax: (+45) 8612 0740
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  • We acknowledge the financial support from the Danish Ministry for Science, Technology and Innovation through the iNANO Center, from the Danish Research Councils, and from the Carlsberg Foundation. R.O. and M.L. acknowledge support through EU individual Marie Curie Fellowship. Computational resources were obtained from the Danish Center for Scientific Computing. R.E.A.K. is grateful to the EPSRC for financial support, Grant No. GR/P01427/01. Finally, we acknowledge the financial support through EU-RTN AMMIST.

Abstract

original image

Binäre Mischungen der komplementären Nucleobasen Guanin (G) und Cytosin (C) auf einer Au(111)-Oberfläche bleiben durch die Bildung von Watson-Crick-Basenpaaren bis zur Desorptionstemperatur der Basen thermisch stabil. Dagegen segregieren binäre Mischungen der nichtkomplementären Basen Adenin (A) und Cytosin beim Erwärmen (siehe STM-Bilder mit DFT-Strukturen).

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