Highly Efficient and Regioselective Platinum(II)-Catalyzed Tandem Synthesis of Multiply Substituted Indolines and Tetrahydroquinolines

Authors

  • Xin-Yuan Liu,

    1. Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong (P.R. China), Fax: (+852) 2857-1586
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  • Chi-Ming Che Prof. Dr.

    1. Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong (P.R. China), Fax: (+852) 2857-1586
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  • This study was supported by The University of Hong Kong (University Development Fund), The Hong Kong Research Grants Council, and The University Grants Committee of the Hong Kong SAR of China (Area of Excellence Scheme, AoE/P-10/01).

Abstract

Ein besonderer Vorteil: Die Platin(II)-katalysierte Tandemcyclisierung von Aminoalkinen mit 1,3-Diketonen ist eine neue und hoch effiziente Methode zur Synthese von Indolinen und Tetrahydrochinolinen (siehe Schema). Unter milden Reaktionsbedingungen werden gute bis sehr gute Ausbeuten sowie hohe Regio- und Chemoselektivitäten erzielt.

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