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Template-Directed Nucleation and Growth of Inorganic Nanoparticles on DNA Scaffolds

Authors

  • Linda A. Stearns,

    1. Center for BioOptical Nanotechnology, The Biodesign Institute and Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 (USA), Fax: (+1) 480-727-0396
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  • Rahul Chhabra,

    1. Center for Single Molecule Biophysics, The Biodesign Institute and Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 (USA), Fax: (+1) 480-727-2378
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  • Jaswinder Sharma,

    1. Center for Single Molecule Biophysics, The Biodesign Institute and Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 (USA), Fax: (+1) 480-727-2378
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  • Yan Liu Prof.,

    1. Center for Single Molecule Biophysics, The Biodesign Institute and Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 (USA), Fax: (+1) 480-727-2378
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  • William T. Petuskey Prof.,

    1. Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 (USA)
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  • Hao Yan Prof.,

    1. Center for Single Molecule Biophysics, The Biodesign Institute and Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 (USA), Fax: (+1) 480-727-2378
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  • John C. Chaput Prof.

    1. Center for BioOptical Nanotechnology, The Biodesign Institute and Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287 (USA), Fax: (+1) 480-727-0396
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  • This work was supported by a grant from the Office of Naval Research (N000140710194G) to H.Y. and J.C.C. We gratefully acknowledge use of facilities in the Leroy Eyring Center for Solid State Science (CSSS) at ASU.

Abstract

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DNA-Origami: Eine DNA-Nanoröhre mit goldbindenden Peptiden kann zu Nanopartikeln bestimmter Größe aus löslichen chemischen Vorstufen führen. Die Peptid-DNA-Nanostruktur diente zum Aufbau einer anorganischen Nanostruktur, in der die Goldnanopartikel entlang der Oberfläche der DNA-Nanoröhre angeordnet sind (siehe Bild). Dies ist ein wichtiger Schritt hin zur Synthese programmierbarer anorganischer Materialien durch Selbstorganisation.

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