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Asymmetric Construction of Polycyclic Indoles through Olefin Cross-Metathesis/Intramolecular Friedel–Crafts Alkylation under Sequential Catalysis

Authors

  • Quan Cai,

    1. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032 (China), Fax: (+86) 21-5492-5087
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  • Zhuo-An Zhao,

    1. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032 (China), Fax: (+86) 21-5492-5087
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  • Shu-Li You Prof. Dr.

    1. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032 (China), Fax: (+86) 21-5492-5087
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  • We thank the National Natural Science Foundation of China (20732006, 20821002), the National Basic Research Program of China (973 Program 2009CB825300), and the Chinese Academy of Sciences for generous financial support.

Abstract

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Abgekürzt: Eine hocheffiziente Kaskadenreaktion (siehe Schema) liefert mit ausgezeichneter Enantioselektivität polycyclische Indole. Die Verknüpfung der beiden Stufen in einer sequentiellen Katalyse ermöglicht den Einsatz leichter zugänglicher Ausgangsmaterialien und macht die Synthese praktikabler. Boc=tert-Butoxycarbonyl.

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