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Programmable Shape-Shifting Micelles


  • We gratefully acknowledge the support of this work by the University of California and from a Henry and Camille Dreyfus Foundation New Faculty Award to N.C.G. We wish to thank Mahealani R. Bautista and Lila K. Habib for their technical assistance, and Norm Olson for his generous assistance. We acknowledge use of the UCSD Cryo-Electron Microscopy Facility, which is supported in part by NIH grant 1S10 RR020016, a gift from the Agouron Institute, UCSD funds provided to Dr. Timothy S. Baker, the Nano-3 facilities at UCSD for use of their AFM instrument, the National Center for Microscopy and Imaging Research at San Diego supported by NIH, and the support of the National Science Foundation under CHE-0741968.


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Amphiphile DNA-Bürsten-Copolymere bilden Micellen, deren Morphologien durch selektive Wechselwirkungen festgelegt sind, die die sterische und elektrostatische Abstoßung in den Micellhüllen beeinflussen. Die Zugabe einer DNA-Sequenz zu den Micellen induziert deren Phasenübergang von der Zylinder- in Kugelformen (siehe Bild).

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