Periplasmic Binding Proteins as Optical Modulators of Single-Walled Carbon Nanotube Fluorescence: Amplifying a Nanoscale Actuator

Authors

  • Prof. Hyeonseok Yoon,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA), Fax: (+1) 617-253-8723
    2. Department of Polymer and Fiber System Engineering, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 500-757 (South Korea)
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    • These authors contributed equally to this work.

  • Dr. Jin-Ho Ahn,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA), Fax: (+1) 617-253-8723
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    • These authors contributed equally to this work.

  • Dr. Paul W. Barone,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA), Fax: (+1) 617-253-8723
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  • Dr. Kyungsuk Yum,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA), Fax: (+1) 617-253-8723
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  • Richa Sharma,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA), Fax: (+1) 617-253-8723
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  • Ardemis A. Boghossian,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA), Fax: (+1) 617-253-8723
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  • Dr. Jae-Hee Han,

    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA), Fax: (+1) 617-253-8723
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  • Prof. Michael S. Strano

    Corresponding author
    1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA), Fax: (+1) 617-253-8723
    • Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (USA), Fax: (+1) 617-253-8723
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  • This work was funded by the MIT Deshpande Center for Technological Innovation and a Beckman Young Investigator award for M.S.S.

Abstract

original image

Glucosesensor: Ein Konjugat aus Glucose-bindendem Protein (GBP) und einer fluoreszenzfähigen einwandigen Kohlenstoff-Nanoröhre (SWNT) kann als optischer Schalter wirken. Das System reagiert auf die Bindung von Glucose mit einer Scharnierbewegung, die eine reversible, hochselektive Excitonenlöschung der SWNT-Fluoreszenz verursacht (siehe Schema).

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