Get access

Regulation of Redox Potential of a Pterin Derivative Bound to a Ruthenium(II) Complex by Intermolecular Hydrogen Bonding with Nucleobases

Authors

  • Yuji Inui,

    1. Department of Material and Life Science, Graduate School of Engineering, Osaka University, and ALCA (JST), 2-1 Yamada-oka, Suita, Osaka 565-0871 (Japan)
    Search for more papers by this author
  • Dr. Soushi Miyazaki,

    1. Department of Material and Life Science, Graduate School of Engineering, Osaka University, and ALCA (JST), 2-1 Yamada-oka, Suita, Osaka 565-0871 (Japan)
    Search for more papers by this author
  • Dr. Kei Ohkubo,

    1. Department of Material and Life Science, Graduate School of Engineering, Osaka University, and ALCA (JST), 2-1 Yamada-oka, Suita, Osaka 565-0871 (Japan)
    Search for more papers by this author
  • Prof. Dr. Shunichi Fukuzumi,

    Corresponding author
    1. Department of Material and Life Science, Graduate School of Engineering, Osaka University, and ALCA (JST), 2-1 Yamada-oka, Suita, Osaka 565-0871 (Japan)
    2. Department of Bioinspired Science, Ewha Womans University, Seoul 120-750 (Korea)
    • Department of Material and Life Science, Graduate School of Engineering, Osaka University, and ALCA (JST), 2-1 Yamada-oka, Suita, Osaka 565-0871 (Japan)
    Search for more papers by this author
  • Prof. Dr. Takahiko Kojima

    Corresponding author
    1. Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8571 (Japan)
    • Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8571 (Japan)
    Search for more papers by this author

  • This work was supported by Grants-in-Aid (Nos. 23750014, 20108010, 21350035, and 20108001), a Global COE program, “The Global Education and Research Center for Bio-Environmental Chemistry” from the Japan Society of Promotion of Science (JSPS), the Ministry of Education, Science, and Technology of Japan, and by KOSEF/MEST through WCU project (R31-2008-000-10010-0) of Korea.

Abstract

original image

Potentialkontrolle: Ein RuII-gebundenes Pterin bildet durch Drei-Punkt-Erkennung ein stabiles Wasserstoffbrückenaddukt mit einem Guaninderivat. Eine große positive Verschiebung des Reduktionspotentials des Pterinliganden von bis zu +320 mV wird beobachtet (siehe Bild). Beim Thyminderivat tritt ein anderer Wasserstoffbrückenmodus auf. Die Regulation von Redoxpotentialen eines Pterin-Coenzyms durch nichtkovalente Wechselwirkungen wird demonstriert.

Get access to the full text of this article

Ancillary