Homogeneous Biogenic Paramagnetic Nanoparticle Synthesis Based on a Microfluidic Droplet Generator

Authors

  • Jae Hwan Jung,

    1. Department of Chemical and Biomolecular Engineering (BK21 program), BioProcess Engineering Research Center, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701 (Republic of Korea) http://nanobiomems.kaist.ac.kr
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    • These authors contributed equally to this work.

  • Dr. Tae Jung Park,

    1. Department of Chemical and Biomolecular Engineering (BK21 program), BioProcess Engineering Research Center, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701 (Republic of Korea) http://nanobiomems.kaist.ac.kr
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    • These authors contributed equally to this work.

  • Prof. Sang Yup Lee,

    Corresponding author
    1. Department of Chemical and Biomolecular Engineering (BK21 program), BioProcess Engineering Research Center, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701 (Republic of Korea) http://nanobiomems.kaist.ac.kr
    • Department of Chemical and Biomolecular Engineering (BK21 program), BioProcess Engineering Research Center, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701 (Republic of Korea) http://nanobiomems.kaist.ac.kr
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  • Prof. Tae Seok Seo

    Corresponding author
    1. Department of Chemical and Biomolecular Engineering (BK21 program), BioProcess Engineering Research Center, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701 (Republic of Korea) http://nanobiomems.kaist.ac.kr
    • Department of Chemical and Biomolecular Engineering (BK21 program), BioProcess Engineering Research Center, Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701 (Republic of Korea) http://nanobiomems.kaist.ac.kr
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  • This work was supported by the R&D Program of MKE/KEIT [10035638] and by the Advanced Biomass R&D Center (ABC) and Intelligent Synthetic Biology Center of Global Frontier Project funded by the Ministry of Education, Science and Technology (2011-0031357, 2011-0031963).

Abstract

original image

Einheitliche Leistung: Ein mikrofluidischer Tröpfchengenerator verkapselt eine stets gleiche Zahl genmanipulierter E.-coli-Zellen mit denselben Konzentrationen an Fe- und Mn-Ionen in Tröpfchen identischer Größe. In den Zellen werden daraufhin biogene paramagnetische FeMn-Nanopartikel synthetisiert.

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