Zuschrift

Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit†

  1. Tomohiro Doura1,
  2. Ryunosuke Hata1,
  3. Dr. Hiroshi Nonaka1,
  4. Prof. Kazuhiro Ichikawa2,
  5. Prof. Shinsuke Sando1,*

Article first published online: 7 SEP 2012

DOI: 10.1002/ange.201202885

Issue

Angewandte Chemie

Angewandte Chemie

Volume 124, Issue 40, pages 10261–10264, October 1, 2012

Additional Information

How to Cite

Doura, T., Hata, R., Nonaka, H., Ichikawa, K. and Sando, S. (2012), Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit . Angew. Chem., 124: 10261–10264. doi: 10.1002/ange.201202885

Author Information

  1. 1

    INAMORI Frontier Research Center, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka (Japan)

  2. 2

    Innovation Center for Medical Redox Navigation, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka (Japan)

*INAMORI Frontier Research Center, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka (Japan)

  1. †

    This work was supported by the NEXT Program and partly by Grant-in-Aid number 22685018 from JSPS. We thank Mr. T. Abe of Oxford Instruments for helpful discussion and technical assistance on the DNP experiments.

Publication History

  1. Issue published online: 26 SEP 2012
  2. Article first published online: 7 SEP 2012
  3. Manuscript Revised: 26 JUN 2012
  4. Manuscript Received: 16 APR 2012

Funded by

  • NEXT Program. Grant Number: 22685018
  • JSPS

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Keywords:

  • Deuterierungen;
  • Dipol-Dipol-Wechselwirkungen;
  • Hyperpolarisierung;
  • Kernresonanz;
  • Spin-Gitter-Relaxation
Thumbnail image of graphical abstract

Das Geheimnis eines langen Lebens: Die vollständig deuterierte 13C-markierte Methoxygruppe (13CD3O) wird als neue funktionelle Gruppe mit langlebiger Hyperpolarisierung für die Entwicklung einer empfindlichen 13C-Kernresonanzsonde beschrieben. Die entsprechende Methode wurde für den Nachweis von hypochloriger Säure genutzt.

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