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A Smart Nanofiber Web That Captures and Releases Cells

Authors

  • Young-Jin Kim,

    1. Materials and Science Engineering, Graduate School of Pure and Applied Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577 (Japan)
    2. Biomaterials Unit, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki 305-0044 (Japan)
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  • Dr. Mitsuhiro Ebara,

    1. Biomaterials Unit, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki 305-0044 (Japan)
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  • Prof. Takao Aoyagi

    Corresponding author
    1. Materials and Science Engineering, Graduate School of Pure and Applied Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577 (Japan)
    2. Biomaterials Unit, International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki 305-0044 (Japan)
    • Materials and Science Engineering, Graduate School of Pure and Applied Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577 (Japan)
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  • We would like to express our gratitude to the Grants-in-Aid for Young Scientists (A) (10013481) from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) Japan. We are grateful to Prof. Allan S. Hoffman (University of Washington) and Dr. John M. Hoffman (Stratos Genomics Inc. in USA) for continued and valuable discussion.

Abstract

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Im Netz gefangen: Photovernetzbare temperaturresponsive polymerbasierte Nanofasernetze wurden synthetisiert, die Zellen aufnehmen, einschließen und abgeben können. Diese Fähigkeit beruht auf der dynamischen Umwandlung der faserigen in eine Hydrogel-artige Struktur durch Einhüllungs- sowie An- und Abschwellprozesse als Reaktion auf externe Temperaturwechsel (siehe Bild).

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