A.E.S. was supported by a Marie Curie Intra-European Fellowship within the 7th European Community Framework Programme (FP7, Project 252247).
Methylene-Bridged Bis(imidazoline)-Derived 2-Oxopyrimidinium Salts as Catalysts for Asymmetric Michael Reactions†
Article first published online: 27 MAY 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 125, Issue 27, pages 7126–7129, July 1, 2013
How to Cite
Sheshenev, A. E., Boltukhina, E. V., White, A. J. P. and Hii, K. K. (2013), Methylene-Bridged Bis(imidazoline)-Derived 2-Oxopyrimidinium Salts as Catalysts for Asymmetric Michael Reactions. Angew. Chem., 125: 7126–7129. doi: 10.1002/ange.201300614
- Issue published online: 21 JUN 2013
- Article first published online: 27 MAY 2013
- Manuscript Revised: 12 MAR 2013
- Manuscript Received: 23 JAN 2013
- Funded Access
- European Community. Grant Number: 252247
- 2In recent years, these two terms are increasingly being used interchangeably. By definition, PTC occurs at a liquid–liquid or a solid–liquid interface (which may be considered as a subset of organocatalysis), but this is not always easy to establish.
- 3For reviews on the development of asymmetric PTCs, see:
- 14Similar compounds were reported in Refs. [7e] and [11a]. They both contain phenyl substituents at C5, obtained in 90 and 92 % ee, respectively.
- 15The relative configurations of 15 c and 16 were established by NOESY experiments (see Supporting Information).
- 17CCDC 919960 [(R,R)-5 b] contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif