We thank Prof. Stephen L. Buchwald (S.L.B.) for encouragement and support. This research was generously sponsored by the National Institutes of Health (GM101762 for A.M.S. and GM046059 for S.L.B.) and also supported by MIT start-up funds and a Damon Runyon Cancer Research Foundation award for B.L.P. C.Z. is a recipient of a Amgen Summer Graduate Research Fellowship. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. We are indebted to Rocco Policarpo, Jingjing J. Ling, Dr. Xiaoli Liao, and Amy Rabideau for technical assistance and helpful discussions, and to Prof. R. John Collier (Harvard) for commenting on the manuscript and contributing some of the laboratory equipment used in these studies. We also thank Prof. Stephen B. H. Kent (U. Chicago) for commenting on this manuscript.
Enzymatic “Click” Ligation: Selective Cysteine Modification in Polypeptides Enabled by Promiscuous Glutathione S-Transferase†
Version of Record online: 12 NOV 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 125, Issue 52, pages 14251–14255, December 23, 2013
How to Cite
Zhang, C., Spokoyny, A. M., Zou, Y., Simon, M. D. and Pentelute, B. L. (2013), Enzymatic “Click” Ligation: Selective Cysteine Modification in Polypeptides Enabled by Promiscuous Glutathione S-Transferase. Angew. Chem., 125: 14251–14255. doi: 10.1002/ange.201306430
- Issue online: 18 DEC 2013
- Version of Record online: 12 NOV 2013
- Manuscript Revised: 28 SEP 2013
- Manuscript Received: 23 JUL 2013
- National Institutes of Health. Grant Numbers: GM101762, GM046059
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