Gold-Catalyzed Intermolecular C[BOND]S Bond Formation: Efficient Synthesis of α-Substituted Vinyl Sulfones


  • We are grateful to the NSF (CAREER-CHE-0844602 and CHE-1228336) and the NSFC (21228204) for financial support.


A general method for the synthesis of α-substituted vinyl sulfones makes use of a combination of a triazole gold complex and gallium triflate. This efficient C[BOND]S bond formation between simple terminal alkynes and sulfinic acids provides access to various α-substituted vinyl sulfones.