Spatial Arrangement and Preparative Organic Synthesis

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Abstract

This review deals with the stereoselective formation of organic compounds. A number of examples of such syntheses, especially those of alkaloids and steroids, are described. An asymmetric synthesis, which avoids the intricacies and wastefulness of optical resolution, has been successful in a few cases only. The procedures of configurational change and of optical resolution, as well as the planning of multi-step stereoselective syntheses, are discussed.

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