Intramolecular [4+2] and [3+2] Cycloadditions in Organic Synthesis

Authors

  • Prof. Dr. Wolfgang Oppolzer

    Corresponding author
    1. Départment de Chimie Organique, Université de Genève, CH-1211, Geneva 4 (Switzerland)
    • Départment de Chimie Organique, Université de Genève, CH-1211, Geneva 4 (Switzerland)
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  • Dedicated to Professor Vladimir Prelog on the occasion of his 70th Birthday

Abstract

Numerous examples of intramolecular cycloaddition of 1,3-dienes, nitrones, and azomethine imines attest the preparative value of this variant for regioselective and stereoselective synthesis of annelated and bridged ring systems. The common features, differences, and limitations of these types of reaction are systematically reviewed.

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